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Post by the Scribe on Jun 28, 2022 19:36:08 GMT
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Post by the Scribe on Jun 28, 2022 20:07:03 GMT
karenmordechai.com/vcahospitals.com/know-your-pet/fenbendazolewww.animalwised.com/panacur-for-cats-fenbendazole-uses-dosage-and-side-effects-3968.htmlWhat is Panacur used for in cats? Panacur in cats serves as an anthelmintic for internal deworming of cats. Panacur is useful for treating gastrointestinal nematode infestations in both kittens and adult felines. The internal parasites that fenbendazole can kill in cats include the following: Toxocara cati Toxascaris leonina Ancylostoma tubaeforme Aelurostrongylus abstrusus Taenia spp. Learn about all the intestinal parasites that affect these animals and the symptoms they produce in our guide to intestinal parasites in cats. Panacur dosage for cats As we have mentioned, there are two main formulations of Panacur for cats, a paste format and a tablet format. Next, we will discuss the doses of each drug formulation for these animals. Panacur oral paste dose 187.5 mg/g Each syringe of oral Panacur can hold up to 4.8 g of paste, which is equivalent to 900 mg of fenbendazole. It has 18 graduations in each syringe, each containing 50 mg of fenbendazole. These are used to ensure the correct Panacur dose is administered. The use of Panacur oral paste is suitable for cats weighing up to 6 kg. If they weigh more, a single syringe is not enough since the dose of this oral paste for adult cats is 75 mg fenbendazole/kg/24h for two consecutive days. Taking into account the mg of fenbendazole per graduation, depending on the weight of the cat, the daily dose of Panacur in adult cats will be as follows: Daily dose for 2 kg cats: 3 graduations over 2 days. Daily dose for cats from 2.1 to 4 kg: 6 graduations over 2 days. Daily dose for cats from 4.1 to 6 kg: 9 graduations over 2 days. In kittens, the fenbendazole dose is 50 mg fenbendazole/kg/ 24h for three consecutive days. This means the daily dose of Panacur in kittens would be as follows: Daily dose for kittens from 1 to 2 kg: 2 graduations for 3 days. Daily dose for kittens from 2.1 to 3 kg: 3 graduations during 3 days. Daily dose for kittens from 3.1 to 4 kg: 4 graduations over 3 days. Daily dose for kittens from 4.1 to 5 kg: 5 graduations during 3 days. Daily dose for kittens from 5.1 to 6 kg: 6 graduations over 3 days. Dose of Panacur tablets 250 mg Panacur tablets can be given with a small amount of their usual food, especially wet food. It can also be dissolved in water and administered with a syringe. The dose of Panacur tablets can be given in a single administration or for three or five consecutive days. The dosage of Panacur tablets in cats is as follows, depending on their frequency of administration: Single dose: 1 tablet for every 2.5 kg of the cat's weight. Dose for three consecutive days: 1 tablet for every 5 kg. Dose for five consecutive days: 1 tablet for every 12.5 kg. If you do not feel confident about giving tablets to a cat, we can help. Here we provide a helpful guide to giving pills to cats. www.rapidtables.com › convert › weightkg to lbs | convert kg to pounds - RapidTables.com 1 kilogram (kg) is equal to 2.20462262185 pounds (lbs). Kilograms (kg) Pounds (lb) Pounds+ounces (lb+oz) 0 kg 0 lb 0 lb 0 oz 0.1 kg 0.220 lb 0 lb 3.527 oz 1 kg 2.205 lb 2 lb 3.274 oz 2 kg 4.409 lb 4 lb 6.548 oz www.metric-conversions.org › weight › kilograms-toKilograms to Pounds - kg to lbs conversion Kilograms to Pounds formula lb = kg * 2.2046 Pounds The pound is a measurement of mass used in the imperial system, and is accepted on a day-to-day basis as a unit of weight (the gravitational www.justagric.com/anti-diarrheal-for-kittens/www.fenbendazole.org/fenbendazole-information/fenbendazole-dosage-guide/
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Post by the Scribe on Oct 9, 2023 17:52:58 GMT
Does Fenbendazole Work for Dogs and Cats?
vitalityscience.com/fenbendazole-may-be-cancer-solution/
Fenbendazole is an effective cancer treatment for dogs and cats. As an anthelminthic (a deworming medication), the drug is often applied in labs where studies are performed on rodents. Well-known research chronicles Fenbendazole’s unexpected effects on the progress and incidence of cancer in lab animals. In other words, through ordinary efforts to keep subjects free of pinworms, researchers noticed that certain cancers failed to grow in the mice treated with Fenbendazole. As a result, many pet owners have come forward saying the medication has helped their pet with cancer help fight it into remission.
Fenbendazole, A Dog Dewormer, Could Be The Answer To Cancer
Mast Cell Tumors, Melanoma, Lymphoma, Bone Cancer (Osteosarcoma), Hemangiosarcoma
Cancer is a terrible illness that has claimed the lives of many pets and people, and pharmaceutical medicine is nowhere near a cure. Currently, most efforts are aimed at managing and reducing cancer symptoms. This has led many cancer researchers and doctors to pursue different medicinal and natural approaches to cancer treatment. One strange yet potentially effective solution is Fenbendazole, a low-cost and very safe dewormer.
What is Fenbendazole?
Fenbendazole is a veterinary medication used for intestinal parasite removal in cats and dogs. Fenbendazole is best known as the counter medication Panacur C. This canine deworming medication has made a name for itself through its excellent use as a cancer treatment for many types of cancer.
Why Does Fenbendazole Have Anti-Cancer Properties?
Microtubules are critical to cell function by providing the necessary structures for the cell to function. As a benzimidazole, Fenbendazole inhibits microtubule polymerization. This means that Fenbendazole can help starve out certain cancers by limiting their spread and growth, potentially allowing the patient to overcome them.
Of course, that is a gross oversimplification. Many studies are being performed on Fenbendazole, and it is too early to state the efficacy of the medication. However, it is also important to state that there have been cases of usage on both animals and people, resulting in a reduction or remission of many cancer types.
For more information on Fenbendazole, dosing, and other information, we have written a post prior that offers a reasonably extensive overview on the topic matter.
The Story of Joe Tippens
Joe Tippens has perhaps the most well-known success story for Fenbendazole. Having heard about the alternative use of Fenbendazole from a scientist who was studying it, he successfully pushed his small cell lung cancer into remission on a regimen now known as the Tippens protocol. It is important to note that there are no notable side effects to Fenbendazole in humans or animals, so cats and humans can take the medication (intended for canines).
Joe has been very vocal about his success with Fenbendazole and his routine and speaking openly of the many people who have similarly attempted taking the medication for them or their pets and saw results. Fenbendazole is a safe alternative to fighting cancer that comes from unlikely origins.
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Post by the Scribe on Oct 9, 2023 17:56:32 GMT
Anti-Worm drug, Fenbendazole, effective at killing cancer cells
Research shows that Fenbendazole, commonly used as a canine deworming drug in veterinary practice, can block sugar uptake, cause apoptosis in cancer cells, reduce tumour size and even help overcome cancer drug resistance, making it another 'repurposed drug' that can be used to treat cancer.
Importantly, this review on Fenbendazole highlights different research studies on several cancers, the dose one might take, what other supplements might help and the frequency of usage; in fact everything you need to know about Fenbendazole as a human anti-cancer drug with minimal side-effects (Updated twice from an article by Chris Woollams, originally in 2016).
Fenbendazole inhibits tumour growth
Back in 2014, a team of researchers at top American Hospital Johns Hopkins was trying to grow tumours by injection in laboratory mice. Except with one group of mice, they failed. The reason they discovered, was that these mice had been de-wormed (1) with an anti-parasitic drug. They read more about the drug, only to find that anti-cancer activity had previously been reported (writes Gilly Bertram).
Fenbendazole comes from a class of drugs called benzimidazoles, which are commonly used in veterinary medicine for anti-worm and parasite treatments. They are used effectively to kill worms such as roundworms, hookworms, whipworms and some tapeworms as well as parasites. Parasitic worms are known as helminths and these drugs are also known as anthelminthic, or antihelminthic, drugs. Fenbendazole is branded under names like Panacur and Safe-Guard.
Research suggests that fenbendazole inhibits tumour growth by inducing apoptosis (cell death) of tumour cells. Researchers are also finding that fenbendazole could be useful for overcoming drug resistance which is a common setback in conventional cancer therapies.
In a 2018 paper published in Nature (2), the authors report that fenbendazole appears to act as a destabilising agent of tubulin in microtubules which are important structural proteins making up the cytoskeleton of cells and these proteins allow the microscopic organs inside our cells (called organelles) to move throughout the cell. These microtubules are present in worms, and also in cancer cells. The researchers conclude that there is evidence of cancer cell death by the modulation of multiple cellular pathways, which may lead to the effective elimination of cancer cells.
The use of anthelminthic drugs with cancer, however, is nothing new.
Scientific literature prior to the 2018 Nature paper demonstrated the effective use of fenbendazole for various types of cancer cells such as Non-small Cell Lung Cancer (3), Lymphoma (4) Metastatic prostate cancer cells (5) and Glioblastoma, or GBM (6).
In the early 90s, another antihelminthic drug called Levamizole was shown as a effective complementary treatment for colon cancer (CRC) and was shown to restore a depressed immune system.
In the 2018 Nature research, Fenbendazole showed an affinity for mammalian tubulin and exerted cytotoxicity to human cancer cells at micromolar concentrations. A further anti-cancer mechanism the researchers found with fenbendazole was that after oral feeding it blocked the uptake of glucose in cancer cells, by affecting p53, GLUT transporters and hexokinase, depriving cancer cells of their primary fuel. This discovery would support the use of fenbendazole as an complementary therapy to chemotherapy and radiotherapy as well as metabolic therapies and potentially a stand alone therapy.
A further study showed prostate cancer cells were killed where fenbendazole was used together with vitamin E succinate (8).
Fenbendazole anti-cancer protocol - amounts and support compounds
Perhaps the most famous anecdotal evidence comes from cancer patient, Joe Tippens, an avid researcher who was given three months to live, who decided to try Panacur with the agreement of his consultant (9). Joe took a combination of nutrients to support fenbendazole, while deciding not to change his diet with his NSCLC. It worked!
Joe Tippens' original protocol for Fenbendazole with lung cancer consts of:
1 gram granules of canine drug ‘Panacur C’, these contain 222mg of fenbendazole; taken 3 days on, 4 days off
Vitamin E Succinate (800IU daily)
Curcumin (600mg daily)
CBD oil (25mg per day)
From our anti-cancer experience, we would suggest patients use ''total' complete vitamin E with all 4 tocopherols and all 4 tocotrienols, instead of the succinate version.
We suggest patients add both Berberine (3 x 500 mg) and Quercetin (2 x 500 mg) to enhance the anti-cancer, sugar reducing and antiinflammatory effects.
We suggest patients add in Retinoic Acid (concentrated vitamin A) - in the Accutane form, it was used by Prof Ben Williams to kill his brain cancer stem cells.
Febendazole toxicity and safety in humans
Although the original clinical approval for fenbendazole was for intestinal parasites and not for cancer, and it is approved for animal use, the drug has already gone through human clinical trials and so all of the clinical trial work related to toxicity has already been done and febendazole has been deemed safe for human consumption for many years.
However, the label for the product approval talks of animals not humans. With animals, it is known that there is a likely interaction with salicylanilides like Niclosamide and Dibromsalan, so we suggest you avoid mixing it with either.
Fenbendazole, Mebendazole and Ivermectin
Fenbendazole appears to have more research on more cancers than Mebendazole does. Mebendazole is licensed for humans and doctors prescribing it won't be 'struck off' for prescribing it to human patients. Ivermectin is also licensed for animals, was said by the FDA to be the safest drug they'd ever tested, and has a somewhat different action. Some experts prescribe all three in conjunction, avoiding the need to take 'days off'. Ivermectin has also been shown in research to attack cancer stem cells. Also used is Retinoic Acid, a concentrated vitamin A, with anti-cancer stem cell properties.
Chris Woollams, former Oxford University Biochemist and a founder of CANCERactive said, "Fenbendazole is yet another example of a cheap, safe drug intended for a specific health condition, which can be repurposed to be used to treat cancer. There is no doubt it has strong properties but oncologists prefer to use Mebendazole for legal reasons, alongside Metformin and Atorvastatin."
Go to: Repurposed drugs as cancer treatments
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